The Community Engagement (CE) program bridges researchers and local communities, building sustainable partnerships to ensure that research initiatives meet real community needs. Researchers benefit by focusing on timely, responsive, culturally relevant research questions, while community members can directly influence research choices and academic-community relations. Moreover, CE provides support that ensures researchers understand the health needs and research barriers of special populations and works to facilitate new academic-community partnerships. As such, CE has developed a range of novel strategies and approaches to engage diverse communities and facilitate meaningful academic-community partnerships.